The Carolina Exploratory Center for Cheminformatics Research

The University of North Carolina at Chapel Hill proposes to establish the Carolina Exploratory Center for Cheminformatics Research to promote multidisciplinary, multi-institutional collaboration among researchers in computational chemistry, chemical biology, datamining, computer science, and statistics to address critical issues in Cheminformatics in the context of Molecular Libraries Initiative (MLI) at NIH. This multi-investigator effort will be coordinated by the Laboratory of Molecular Modeling and the Cheminformatics Research Resource at UNC-Chapel Hill, led by Professor Alexander Tropsha. In the course of the planning stage, we shall develop technical strategies and administrative infrastructure for CECCR integrating most essential components of Cheminformatics resources. These components include, but not limited to: • the procedures to calculate molecular descriptors • biologically relevant diversity and similarity metrics • data analytical tools • specialized methodologies for chemical library design and virtual screening • rigorously validated biological and ADMETox property predictors Incorporating these components, the CECCR will establish and maintain an integrated publicly available Carolina Cheminformatics Workbench (C-ChemBench) to support experimental chemists in the Chemical Methodology and Library Development (CMLD) Centers and quantitative biologists in the Molecular Libraries Screening Centers Network (MLSCN). The Workbench which is intended as a data analytical extension to the PubChem will enable researchers to mine available chemical and biological data to rationally design new compounds or compound libraries with significantly enhanced hit rates in the corresponding screening experiments. To begin the implementation of current and developing best practices in Cheminformatics research and translate them into advanced computational tools, the planning stage for the CECCR will focus on the following Specific Aims: 1. Establish Productive Collaborating Environment for Participating Laboratories; 2. Investigate Multidisciplinary Approaches to Key Cheminformatics Issues; 3. Build a Prototypic Web Based Cheminformatics Workbench (C-ChemBench)

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http://ceccr.unc.edu

Chaotic Maps

Chaotic dynamics of nonlinear maps is explained and illustrated by means of tiny Java applets

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http://www.ibiblio.org/e-notes/Chaos/contents.htm

TechniCalc

TechniCalc is an alliance of sites devoted to the use of handheld computers and calculators in industry and academics.

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English

http://www.technicalc.org

GetWiki

GetWiki is a wiki document collaboration and discussion site for a wide variety of intellectual topics in the Humanities and Sciences, from Metaphysics to Metadata, Philosophy to Technology. The wiki runs on the latest GetWiki collaboration software.

getwiki

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English

http://getwiki.net

Transoxiana

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697

English,Italian,Spanish,Russian

http://www.transoxiana.org

The Celestia Motherlode

This site is based around Celestia, a free, 3-D, real-time space simulator. Celestia is an awesome experience for anyone interested in physics, astronomy, or cosmology. The Motherlode is a collection of surface textures, models and astronomical data, which enables Celestia users to easily create their own detailed, realistic copies of the known (and imagined) universe.

celestia

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http://celestiamotherlode.net

3D Game of Life

An animated 3D generalization of John Conway's Game of Life written in Java, with examples.

demidov

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English

http://www.ibiblio.org/e-notes/Life/Game.htm

More Than Math

More Than Math integrates the visual arts into the 3rd, 4th and 5th grade mathematics curriculum using works of art from the collection of the Asheville Art Museum as the basis for problematic mathematical tasks using NC Standard Course of Study goals and objectives. More Than Math introduces and explores concepts shared by mathematics and the visual arts such as pattern, symmetry, proportion, perspective, balance and geometric form and stresses the importance of each individual’s perspective.A project of the Asheville Art Museum with support from the UNC-CH School of Education. Flash applets created by Drew Johnston.

This site was created partially in Flash, you’ll need to allow Flash in order to view it. See this exhibit for more details https://www.ibiblio.org/catalog/exhibits/show/a-brief-history-of-flash/a-brief-history-of-flash

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http://www.morethanmath.org

An Interactive Introduction to Splines

Bezier, B-spline, NURBS, and many other spline curves and surfaces with interactive 2D Java applets and VRML

demidov

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http://www.ibiblio.org/e-notes/Splines/Intro.htm

The Mandelbrot and Julia sets Anatomy

A virtual investigation with interactive, animated fractals, articles and fractal math equations

demidov

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http://www.ibiblio.org/e-notes/MSet/Contents.htm